Arti Tripathi, PhD

Staff Scientist

Arti Tripathi joined the J. Craig Venter Institute (JCVI) as a staff scientist in the Synthetic Biology department. Prior to JCVI, Dr. Tripathi was a postdoctoral fellow at the National Institutes of Health (NIH) where she studied the regulated proteolysis of a central regulator of the bacterial stress response, the RNA polymerase sigma factor (RpoS). Before NIH, she conducted research on bioengineering an archaeon for the production of liquid biofuel at Pennsylvania State University. Dr. Tripathi earned a PhD in molecular biophysics from the Indian Institute of Science, India. Her doctoral thesis focused on the determinants for protein stability, structure, and function. She also investigated the role of toxin-antitoxin modules in bacterial physiology and antibiotic tolerance.


Cross-Genus "Boot-Up" of Synthetic Bacteriophage in Staphylococcus aureus by Using a New and Efficient DNA Transformation Method.
Applied and environmental microbiology. 2022-02-08; 88.3: e0148621.
PMID: 34818102
Structural basis for inhibition of a response regulator of σS stability by a ClpXP antiadaptor.
Genes & development. 2019-06-01; 33.11-12: 718-732.
PMID: 30975721
Molecular Determinants of Temperature-Sensitive Phenotypes.
Biochemistry. 2019-04-02; 58.13: 1738-1750.
PMID: 30843689
Contribution of the Chromosomal ccdAB Operon to Bacterial Drug Tolerance.
Journal of bacteriology. 2017-10-01; 199.19:
PMID: 28674066
Cell biology: Phosphate on, rubbish out.
Nature. 2016-11-03; 539.7627: 38-39.
PMID: 27808186
Molecular Determinants of Mutant Phenotypes, Inferred from Saturation Mutagenesis Data.
Molecular biology and evolution. 2016-11-01; 33.11: 2960-2975.
PMID: 27563054
Reversing methanogenesis to capture methane for liquid biofuel precursors.
Microbial cell factories. 2016-01-14; 15.11.
PMID: 26767617
MazF-induced growth inhibition and persister generation in Escherichia coli.
The Journal of biological chemistry. 2014-02-14; 289.7: 4191-205.
PMID: 24375411
Residue specific contributions to stability and activity inferred from saturation mutagenesis and deep sequencing.
Current opinion in structural biology. 2014-02-01; 24.63-71.
PMID: 24721454
Additional role for the ccd operon of F-plasmid as a transmissible persistence factor.
Proceedings of the National Academy of Sciences of the United States of America. 2012-07-31; 109.31: 12497-502.
PMID: 22802647
Protein model discrimination using mutational sensitivity derived from deep sequencing.
Structure (London, England : 1993). 2012-02-08; 20.2: 371-81.
PMID: 22325784